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With regard to the claim that VANFLYTA® reduced mortality rate regardless of receiving an allo-HSCT or not, we note that the evidence provided in support was based on data from the QUANTUM First trial, which compared VANFLYTA® to placebo rather than to RYDAPT® and we question whether this type of comparison can provide evidence to support a finding of improved outcomes compared to previously available therapy

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Is this a concept that you think, I mean certainly most tumors, if they become metastatic, you just can't give enough chemo, you can't give enough targeted therapy, enough immunotherapy, doesn't matter what it is